{"id":1692,"date":"2020-02-20T14:57:41","date_gmt":"2020-02-20T14:57:41","guid":{"rendered":"https:\/\/molbio-api.massgeneral.org\/?post_type=labs&p=1692"},"modified":"2022-09-30T20:21:32","modified_gmt":"2022-09-30T19:21:32","slug":"sadreyev-lab","status":"publish","type":"labs","link":"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/","title":{"rendered":"Sadreyev Lab"},"template":"","meta":[],"class_list":["post-1692","labs","type-labs","status-publish","hentry"],"acf":{"title_override":"Sadreyev Lab","header_text":"","header_image":false,"has_contents":false,"header_button_text":"","header_button_link":"","new_tab":false,"featured_image":{"ID":5572,"id":5572,"title":"Sandreyev Lab","filename":"Sandreyev-Lab.jpg","filesize":78063,"url":"https:\/\/molbio-api.massgeneral.org\/wp-content\/uploads\/2020\/02\/Sandreyev-Lab.jpg","link":"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/sandreyev-lab\/","alt":"Sandreyev Lab","author":"1","description":"","caption":"","name":"sandreyev-lab","status":"inherit","uploaded_to":1692,"date":"2021-04-01 16:44:41","modified":"2021-04-01 16:44:48","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/molbio-api.massgeneral.org\/wp-includes\/images\/media\/default.png","width":600,"height":900,"sizes":{"thumbnail":"https:\/\/molbio-api.massgeneral.org\/wp-content\/uploads\/2020\/02\/Sandreyev-Lab-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/molbio-api.massgeneral.org\/wp-content\/uploads\/2020\/02\/Sandreyev-Lab-200x300.jpg","medium-width":200,"medium-height":300,"medium_large":"https:\/\/molbio-api.massgeneral.org\/wp-content\/uploads\/2020\/02\/Sandreyev-Lab.jpg","medium_large-width":600,"medium_large-height":900,"large":"https:\/\/molbio-api.massgeneral.org\/wp-content\/uploads\/2020\/02\/Sandreyev-Lab.jpg","large-width":600,"large-height":900,"1536x1536":"https:\/\/molbio-api.massgeneral.org\/wp-content\/uploads\/2020\/02\/Sandreyev-Lab.jpg","1536x1536-width":600,"1536x1536-height":900,"2048x2048":"https:\/\/molbio-api.massgeneral.org\/wp-content\/uploads\/2020\/02\/Sandreyev-Lab.jpg","2048x2048-width":600,"2048x2048-height":900}},"featured_content":"

Ruslan Sadreyev, PhD
\n<\/strong>Assistant Professor
\nHarvard Medical School<\/p>\n

\n

Contact
\n<\/strong>sadreyev@molbio.mgh.harvard.edu<\/a>
\n<\/strong><\/p>\n

MGH Department of Molecular Biology
\nSimches Research Center
\n185 Cambridge Street
\nBoston, MA 02114<\/p>\n

\n

Website
\n<\/strong>Sadreyev Lab<\/a><\/p>\n

\n

Publications
\n<\/strong>NCBI<\/a><\/p>\n","flexible_content":[{"acf_fc_layout":"title_block","size":"medium","text":"Quantitative analyses of chromatin regulation."},{"acf_fc_layout":"text_block","text_block":"

We focus on computational analyses of large-scale biomedical data with the aim to better understand molecular mechanisms of genome regulation and pathophysiology of disease. We are particularly interested in the role of chromatin in the regulation of gene activity and other genomic functions. \u00a0We combine large-scale approaches of quantitative epigenomics with more focused approaches of biochemistry and genetics to test our computational hypotheses. When necessary, we develop new computational methods to advance these analyses.
\nA separate but overlapping area of our interest is quantitative analysis of electronic medical records, which can provide new insights into disease development, help improve diagnosis, and inform patient\u2019s treatment. We are especially interested in the computational analysis of clinical measurements widely performed in large groups of patients, for example standard blood tests.
\nOur lab is involved in intensive collaborations with multiple experimental and clinical research groups that focus on both fundamental and medical aspects of genomic and epigenomic regulation in healthy cells and disease.<\/p>\n"}],"header_button_is_top":false,"header_button_icon":"","background_color":"white","background_anchor_point":""},"yoast_head":"\nSadreyev Lab - Molbio<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sadreyev Lab - Molbio\" \/>\n<meta property=\"og:url\" content=\"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/\" \/>\n<meta property=\"og:site_name\" content=\"Molbio\" \/>\n<meta property=\"article:modified_time\" content=\"2022-09-30T19:21:32+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/\",\"url\":\"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/\",\"name\":\"Sadreyev Lab - Molbio\",\"isPartOf\":{\"@id\":\"https:\/\/molbio-api.massgeneral.org\/#website\"},\"datePublished\":\"2020-02-20T14:57:41+00:00\",\"dateModified\":\"2022-09-30T19:21:32+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/molbio-api.massgeneral.org\/labs\/sadreyev-lab\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/molbio-api.massgeneral.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Labs\",\"item\":\"https:\/\/molbio-api.massgeneral.org\/labs\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Sadreyev Lab\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/molbio-api.massgeneral.org\/#website\",\"url\":\"https:\/\/molbio-api.massgeneral.org\/\",\"name\":\"Molbio\",\"description\":\"The Department of Molecular Biology at MGH. 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